Rosacea is a long-term inflammatory skin condition that affects millions of people worldwide. It commonly causes persistent facial redness, flushing, visible blood vessels and, in many cases, acne-like bumps and spots.
If you've been diagnosed with papulopustular rosacea, your doctor may prescribe Soolantra (ivermectin 1% cream). It has become one of the most widely recommended topical treatments for rosacea because it targets both inflammation and one of the factors believed to contribute to flare-ups.
In this guide, we'll explain how ivermectin works, who it is suitable for, and what results you can expect.
What Is Soolantra?
Soolantra contains 1% ivermectin, a prescription-only topical cream used to treat the inflammatory lesions (papules and pustules) associated with rosacea in adults.
Unlike treatments that simply reduce redness, ivermectin works by addressing inflammation while also reducing the number of Demodex mites, tiny organisms that naturally live on the skin but are often found in higher numbers in people with rosacea.
How Does Ivermectin Work?
Researchers believe rosacea develops due to a combination of factors, including:
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An overactive immune response
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Skin barrier dysfunction
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Genetics
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Environmental triggers
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Increased numbers of Demodex mites in some individuals
Ivermectin works in two important ways:
Reduces Inflammation
Ivermectin has anti-inflammatory properties that help calm irritated skin and reduce red, inflamed bumps.
Helps Reduce Demodex Mites
Although Demodex mites are naturally present on human skin, higher numbers have been associated with certain forms of rosacea. Ivermectin helps reduce these mites, which may lessen inflammation in susceptible individuals.
What Symptoms Can Soolantra Improve?
Soolantra is primarily prescribed for inflammatory rosacea and may help reduce:
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Red bumps (papules)
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Pus-filled spots (pustules)
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Skin inflammation
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Overall skin irritation
It is important to note that Soolantra is not specifically designed to treat persistent facial redness or visible thread veins.
How to Use Soolantra
For best results:
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Cleanse the face using a gentle, fragrance-free cleanser.
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Pat the skin completely dry.
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Apply a thin layer of Soolantra once daily, usually in the evening, unless otherwise advised by your healthcare professional.
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Avoid the eyes, lips and inside the nose.
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Wash your hands after application.
Use the cream exactly as prescribed.
When Will You See Results?
Rosacea treatments require patience.
Typical improvement timeline:
Weeks 2–4
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Skin irritation may begin to settle.
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New inflammatory spots may reduce.
Weeks 6–8
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Noticeable improvement in bumps and blemishes.
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Skin often feels calmer.
Around 12 Weeks
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Many patients experience significant improvement in inflammatory lesions when treatment is used consistently.
Even if improvement isn't immediate, continuing treatment as directed is important unless advised otherwise by your healthcare provider.

Common Side Effects
Most people tolerate Soolantra well.
Possible side effects include:
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Mild burning
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Temporary stinging
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Dry skin
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Mild irritation
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Itching
These effects are often temporary and improve as treatment continues.
If you develop severe irritation or an allergic reaction, stop using the cream and seek medical advice.
Can You Wear Makeup?
Yes.
Many people with rosacea choose to apply moisturiser followed by makeup once the cream has fully absorbed.
Choosing fragrance-free, non-comedogenic products may help minimise irritation.
Skincare Tips While Using Soolantra
A gentle skincare routine can help support treatment.
Recommended routine:
Morning
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Gentle cleanser
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Moisturiser
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Broad-spectrum SPF 30 or higher
Evening
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Gentle cleanser
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Soolantra
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Moisturiser if needed
Avoid harsh exfoliants, abrasive scrubs and heavily fragranced skincare products if they trigger irritation.
Rosacea Triggers to Watch For
Although everyone's triggers are different, common causes of flare-ups include:
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Sun exposure
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Hot drinks
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Alcohol
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Spicy foods
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Stress
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Hot baths
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Extreme temperatures
Keeping a diary can help identify personal triggers.
Frequently Asked Questions
Is Soolantra a steroid?
No.
Soolantra contains ivermectin and does not contain corticosteroids.
Can I use moisturiser with Soolantra?
Yes. A gentle moisturiser can help support the skin barrier and reduce dryness.
Is Soolantra available without a prescription?
No. In Ireland, Soolantra is a prescription-only medicine and should be used under the guidance of a healthcare professional.
Does Soolantra cure rosacea?
Rosacea is a chronic skin condition, so there is currently no cure. However, treatments such as Soolantra can help manage symptoms and reduce flare-ups when used consistently.
Final Thoughts
Soolantra (ivermectin 1% cream) has become an important treatment option for inflammatory rosacea because it targets both inflammation and one of the contributing factors linked to the condition.
Combined with a gentle skincare routine, daily sun protection and avoiding personal triggers, many people experience clearer, calmer skin over time.
If you think Soolantra may be suitable for you, speak with your GP, dermatologist or prescribing healthcare professional to discuss the most appropriate treatment plan.